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Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!
In the dark ages of T cell biology, we considered two fates for differentiated CD4+ T cells: T helper (Th)1 and Th2 cells. Now we know that the reality is much more complex and interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows that the IL-17-related cytokine IL-25 is essential for Th2 responses in two infectious disease models.
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ژورنال
عنوان ژورنال: L Homme
سال: 2004
ISSN: 0439-4216,1953-8103
DOI: 10.4000/lhomme.24776